Figure 4. Differentiation of epithelial cells is repressed in tamoxifen-treated Klf5ERΔ mouse colon and small intestine compared with controls.
Day 5 tamoxifen-treated colon tissue sections stained with Alcian blue (as blue stain in panels A and B) and similarly treated small intestinal tissues stained with lysozyme (as brown stain in panels C and D). Panels A & C represent control Klf5fl/fl mice, while Panels B & D represents Klf5ERΔ tissues. There was a significant reduction in Alcian blue and lysozyme staining in Klf5ERΔ tissues (Panels B & D) compared to controls (Panels A & C).