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. Author manuscript; available in PMC: 2014 Mar 12.
Published in final edited form as: Eur J Med Chem. 2012 Dec 20;60:395–409. doi: 10.1016/j.ejmech.2012.12.027

Table 1.

4- and 5-substituted 1-phenylnaphthalenes.

graphic file with name nihms557365t1.jpg
X Y R1 R2
1 CH2NH2 H H t-butyl
2 CH2CH2NH2 H H t-butyl
3 CH2NC(NH2)2 H H t-butyl
4 CH2CH2NC(NH2)2 H H t-butyl
5 H CH2NH2 H t-butyl
6 H CH2CH2NH2 H t-butyl
7 H CH2CNH(NH2) H t-butyl
8 H CH2NC(NH2)2 H t-butyl
9 H CH2CH2NC(NH2)2 H t-butyl
10 H CH2NC(NH2)2 H cyclopropyl
11 H CH2NC(NH2)2 H Cl
12 H CH2NC(NH2)2 H Br
13 H CH2CNH(NH2) H CF3
14 H CH2NC(NH2)2 H CF3
15 H CH2CH2NC(NH2)2 H CF3
16 H CH2CH2NH2 OCH3 CF3
17 H CH2CH2NH2 OH CF3
18 H CH2NC(NH2)2 OCH3 CF3
19 H CH2CH2NC(NH2)2 OCH3 CF3