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Diabetes in C57BL/6 and non-obese diabetic (NOD) mice: comparison of clinical and histopathological parameters.
| C57BL/6: day 21 (15 animals per group) |
NOD: week 29 (11 animals per group) |
|||||
|---|---|---|---|---|---|---|
| STZ | BCG – STZ | BCG/DNAhsp65 – STZ | NOD | BCG – NOD | BCG/DNAhsp65 – NOD | |
| Glycaemic levels (mg/dl) | 322 | 366 | 338 | 287 | 186 | 159 |
| Diabetes incidence (%) | 100 | 100 | 100 | 64 | 27 | 0 |
| Insulitis score 3 (%) | 2 | 6 | 14 | 50 | 20 | 17 |
BCG: bacille Calmette–Guérin; STZ: streptozotocin.
