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. 2013 Oct 15;170(5):1027–1040. doi: 10.1111/bph.12326

Figure 1.

Figure 1

PWL in response to radiant heat. Animals were treated with i.pl. CFA (150 μL) on day 0, and i.t. BAM8-22 (3.3, 10.0 and 30.0 nmol) or MSH (1.7, 5.0 and 15.0 nmol) on days 0 and 1. PWL was measured on days 0, 1 and 2 prior to any injections in (A) and (C). PWL was also measured on day 1 after the injection of BAM8-22 (B) or MSH (D). In (B) and (D), PWL was calculated as percentage of pretreatment baseline PWL (100%). *P < 0.05, **P < 0.01, ***P < 0.001: compared with saline group (A and C) or pretreatment baseline (B and D).