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Effect of CTAP on BAM8-22-induced anti-nociceptive responses. CFA was injected i.pl. on day 0 and i.t. BAM8-22 (30 nmol), or saline was administered i.t. on days 0 and 1. CTAP (10 nmol) or saline was given i.t. at 4 h (A) or 48 h (B). #P < 0.05, ##P < 0.01 and ###P < 0.001 compared with pre-CTAP value. ***P < 0.001 compared with CFA + BAM8-22 + CTAP group.
