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. 2013 Oct 15;170(5):1027–1040. doi: 10.1111/bph.12326

Figure 7.

Figure 7

Influence of i.t. BAM8-22 on mRNA levels of MOR as well as POMC and β-endorphin content in the spinal dorsal horn and/or DRG. CFA was injected i.pl. in the right hindpaw on day 0, and BAM8-22 (30 nmol) or saline was administered i.t. on days 0 and 1. The lumbar spinal dorsal horn and L4-6 DRG were collected on day 2. mRNA levels of MOR (A and B) and POMC (C and D) and β-endorphin content (E) in the spinal cord and/or DRG were assayed. The data represent normalized averages derived from the threshold cycles in quantitative PCR. *P < 0.05 compared with the contralateral side. #P < 0.05, ##P < 0.0; compared with saline group. n = 5.