Figure 2. Monovalent and divalent saturation level as a function of concentration.

The level of antibody saturation upon binding to oligomers is shown as a black line and binding to monomers is shown as a red line. The vertical dotted lines indicate the concentrations where the saturation level of binding to the oligomer is above 50% while the monovalent saturation level remains below 2%. (A) mAB-O, (B) mAB-M, (C) ASyO2, (D) ASyO5, (E) ASyM.