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. 2014 Mar 11;9(3):e91081. doi: 10.1371/journal.pone.0091081

Table 1. Annotated transcripts differentially expressed in AMØs, MoDCs and BMCs at 0 h, 1 h and 24 h p.i. following PCV2b infection.

Cell type Time-point p.i. Gene symbol FC Gene description
AMØs 0 h PRDX6 2.58 Peroxiredoxin-6
1 h TNF 2.32 Tumor necrosis factor
MoDCs 1 h IL1B 6.47 Interleukin 1-beta
CXCL2 4.66 Chemokine (C-X-C motif) ligand 2
IL8 4.4 Interleukin 8
TNF 4.17 Tumor necrosis factor
IER3 3.4 immediate early response 3
CCL4 3.37 Chemokine (C-C motif) ligand 4
ADM 3.27 adrenomedullin
IL1A 3.2 Interleukin-1 alpha
MAP3K8 2.91 Mitogen-activated protein kinase 8
BTG2 2.35 B-cell translocation gene 2
RND3 2.29 rho Family GTPase 3
JAG1 2.15 jagged 1
TNFAIP3 2.14 tumor necrosis factor, alpha-induced protein 3
IRF1 2.1 interferon regulatory factor 1
NFKBIA 2.08 NF-kappa-B inhibitor alpha
IRG1 2.01 immune-responsive gene 1 protein homolog
MFSD2A 1.98 Major facilitator superfamily domain-containing protein 2
OSM 1.86 oncostatin M
HBEGF 1.84 heparin-binding EGF-like growth factor
CCL20 1.82 chemokine (C-C motif) ligand 20
STAB1 1.82 stabilin 1
TOB1 1.73 transducer of ERBB2, 1
SLC2A6 1.71 solute carrier family 2 (facilitated glucose transporter), member 6
CSRNP1 1.68 cysteine-serine-rich nuclear protein 1
MoDCs 24 h VDAC1P5 4.06 voltage-dependent anion channel 1 pseudogene 5
S100A9 3.3 S100 calcium binding protein A9
COX3 3.21 cytochrome oxidase 3
ARHGAP25 2.85 Rho GTPase activating protein 25
SLC25A6 2.71 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
RPL32 2.46 ribosomal protein L32
MRPL18 2.28 mitochondrial ribosomal protein L18
RTN4 2.25 reticulon 4
TGH2 2.17 tissue transglutaminase homologue
PDLIM1 2.1 PDZ and LIM domain 1
PLCXD1 1.99 phosphatidylinositol-specific phospholipase C, X domain containing 1
CASP10 1.78 caspase 10, apoptosis-related cysteine peptidase
RANBP1 1.77 RAN binding protein 1
VDAC2 1.66 voltage-dependent anion channel 2
FCN1 −1.75 ficolin (collagen/fibrinogen domain containing) 1
BTC −1.77 betacellulin
ITGB5 −2.03 integrin, beta 5
PIK3IP1 −2.05 phosphoinositide-3-kinase interacting protein 1
SEPP2 −2.08 septin 2
RNASE4 −2.27 ribonuclease, RNase A family, 4
DKK3 −2.29 dickkopf 3 homolog
DUOXA2 −3 dual oxidase maturation factor 2
BMCs 0 h PLDN 1.56 pallidin homolog
BMCs 24 h Es25 3.9 Esterase 25
IGSF8 2.78 immunoglobulin superfamily, member 8
PTGES 2.54 prostaglandin E synthase
TMEM237 −1.6 transmembrane protein 237
MMRN2 −1.72 multimerin 2
MYL1 −2.27 myosin, light chain 1
PEG10 −2.57 paternally expressed 10

A total of 93 transcripts showed differential expression. Annotated transcripts are listed in each immune cell subset from the highest to the lowest fold-change at the different time points p.i.