Table 4. Downstream effect analysis of differentially-expressed genes involved in apoptosis in MoDCs 1 h and 24 h post PCV2b challenge.
Cell Type | ID | FC | Predicted Effect of Gene on Apoptosis |
MoDCs 1 h p.i. | |||
IL1B | 6.470 | Increased | |
IL8 | 4.400 | Increased | |
TNF | 4.170 | Increased | |
IER3 | 3.400 | Increased | |
IL1A | 3.200 | Increased | |
MAP3K8 | 2.910 | Increased | |
IRF1 | 2.100 | Increased | |
NFKBIA | 2.080 | Increased | |
OSM | 1.860 | Increased | |
HBEGF | 1.840 | Affected | |
CXCL2 | 4.660 | Decreased | |
CCL4 | 3.370 | Decreased | |
ADM | 3.270 | Decreased | |
BTG2 | 2.350 | Decreased | |
RND3 | 2.290 | Decreased | |
JAG1 | 2.150 | Decreased | |
TNFAIP3 | 2.140 | Decreased | |
TIMP1 | 1.770 | Decreased | |
INSR | 1.600 | Decreased | |
MoDCs 24 h p.i. | |||
S100A9 | 3.3 | Increase | |
SLC25A6 | 2.71 | Increase | |
RTN4 | 2.25 | Increase | |
CASP10 | 1.78 | Increase | |
RANBP1 | 1.77 | Affects | |
VDAC2 | 1.66 | Increase | |
BTC | −1.77 | Increase | |
ITGB5 | −2.03 | Decrease | |
PIK3IP1 | −2.05 | Decrease | |
DKK3 | −2.29 | Decrease |