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. 2014 Mar 11;9(3):e91246. doi: 10.1371/journal.pone.0091246

Table 3. Effects of the copper (II) complex on liver function in AOM-induced colon cancer.

Groups Total protein (g/L) Albumin (g/L) AST (IU/L) ALT (IU/L) GGT(IU/L)
Negative control group 67.32±0.34 12.27±0.54 207.2±2.53 63±2.38 5.5±0.3
Cancer control group 69.5±0.39 9.0±0.31 229.6±7.2 69.5±0.68 3.7±0.6
Positive control group 73.6±2.1 11.3±0.89 182.0±4.5 50.0±0.92 6.1±0.48
Cu(BrHAP)2 (2.5 mg/kg) 68.5±0.67 10.5±0.4 209.5±6.1 64.2±0.63 4.1±0.1
Cu(BrHAP)2 (5 mg/kg) 70.9±1.1 11.3±0.42 212.0±10.6 62.0±3.4 4.3±0.32

The values are expressed as the mean ± the SEM There were no significant differences between groups. The significance value was set at P < 0.05 compared to the cancer control group. TB: total bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: g-glutamyl transferase.