Table 1. Sensitivity of NPC cells treated in vitro with Abexinostat or CDDP used as single agents.
Cell type | Abexinostat IC50 | CDDP IC50 | ||
MTT/WST | Clonogenic assay | MTT/WST | Clonogenic assay | |
MRC5 | 500 nM | 15 µM | ||
HONE1 | 400 nM | 400 nM | 3 µM | 1.8 µM |
CNE1 | 700 nM | 300 nM | 3 µM | 1.8 µM |
C666-1 | 220 nM | 70 nM | 10 µM | 4 µM |
C15 | 200 nM | 5 µM | ||
C17 | 150 nM | 8 µM |