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. 2014 Mar 11;9(3):e91325. doi: 10.1371/journal.pone.0091325

Table 1. Sensitivity of NPC cells treated in vitro with Abexinostat or CDDP used as single agents.

Cell type Abexinostat IC50 CDDP IC50
MTT/WST Clonogenic assay MTT/WST Clonogenic assay
MRC5 500 nM 15 µM
HONE1 400 nM 400 nM 3 µM 1.8 µM
CNE1 700 nM 300 nM 3 µM 1.8 µM
C666-1 220 nM 70 nM 10 µM 4 µM
C15 200 nM 5 µM
C17 150 nM 8 µM