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. Author manuscript; available in PMC: 2014 Mar 12.
Published in final edited form as: Diabetes Manag (Lond). 2013 May;3(3):217–223. doi: 10.2217/dmt.13.17

Figure 2. How viral infections stop Type 1 diabetes; TGF-β-mediated invigoration of a bystander Treg population, as well as downregulation of autoaggressive T cells through virally mediated induction of PD-1L and TNF-α.

DC: Dendritic cell; LCMV: Lymphocytic choriomeningitis virus.

Reproduced with permission from [43].

Figure 2