Table 6. Local and systemic reactions following the pre-school PCV-13 booster at 40 months of age.

		PCV-13 (N = 55)		PCV-7 (N = 49; 48 for T°)			Both groups (N = 104; 103 for T°)
Reaction	Level	N	Proportion	N	Proportion	P value **	N	Proportion
Redness	Any	26	47%	20	41%	0.5566	46	44%
	Severe ≥5 cm	3	6%	1	2%		4	4%
Swelling	Any	8	15%	14	29%	0.0959	22	21%
	Severe ≥5 cm	1	2%	1	2%		2	2%
Hardness	Any	10	18%	16	33%	0.1136	26	25%
	Severe ≥5 cm	0	0%	0	0%		0	0%
Tenderness	Any	32	58%	28	57%	1.0000	60	58%
	Discomfort during routine activities	9	16%	6	12%		15	14%
	Interfering with limb movement	2	4%	2	4%		4	4%
Poor appetite	Appetite as usual	45	82%	40	82%	0.2322	19	18%
	Eating less/no effect on normal activity	6	11%	9	18%		15	14%
	Interfering with normal activity	3	6%	0	0%		3	3%
	Not eating at all	1	2%	0	0%		1	1%
Irritability	Behavior as usual	27	49%	34	70%	0.1925	43	41%
	More irritable/no effect on normal activity	18	33%	11	22%		29	28%
	Interfering with normal activity	6	11%	2	4%		8	8%
	Preventing normal activity	4	7%	2	4%		6	6%
Axillary Temperature	<38.0°C	55	100%	45	94%	0.0978	100	97%
	38.0–38.4°C	0	0%	2	4%		2	2%
	38.5–38.9°C	0	0%	1	2%		1	1%

**Fisher’s Exact Test.