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. 2014 Mar 11;9(3):e92351. doi: 10.1371/journal.pone.0092351

Figure 1. Cathepsin B (CB) expression in human esophageal tissues and two cell lines.

Figure 1

Positive expression was observed in intraepithelial neoplasia (IN) I(b), IN II(c), IN III (d), tumor in situ (e) and esophageal squamous cell carcinoma (f) but not in normal esophageal mucosa (a). (g) Eca-109 cells (human esophageal squamous cell carcinoma cell line) had a high level of CB expression, but Het-1A cells (normal human esophageal epithelial cell line) had no CB expression. β-actin was used as an internal control. Original magnification, 100×.