Fig. 3.

Telmisartan prevents glutamate-induced inflammation in rat CGCs. CGCs were treated with 1 µM telmisartan (Telm) or vehicle, and two hours later were exposed for different time points to 100 µM glutamate (Glut). The gene expressions of IL-1β (A) and COX-2 (B) were determined by qPCR as described in Materials and Methods. Results are means ± SEM of at least three independent experiments. **P < 0.01, ***P < 0.001 Glut vs. Glut+Telm.