Figure 1.

Fra-2 ^Δadip mice have decreased body weight and adipocyte number. (a) Body weight of mice and fat content from controls and Fra-2 ^Δadip mice at 6 weeks after tamoxifen injections with mice receiving normal diet (ND) or high-fat diet (HFD) (n=4–5). (b) Fat pad per body weight of Fra-2^Δadip mice and littermate controls at 6 weeks after tamoxifen injections with mice receiving ND or HFD (n=4–5). (c) Hematoxylin and eosin staining of fat pad tissue from Fra-2^Δadip mice and littermate controls at 6 weeks after tamoxifen injection receiving ND or HFD. Magnification × 20, bars=100 μm. (d) Adipocyte cells area and number of adipocyte per area of Fra-2^Δadip mice and littermate controls at 6 weeks after tamoxifen injections with mice under ND or HFD (n=4–10). Bars represent mean values±S.D. Statistical analyses: *P<0.05, **P<0.01, ***P<0.001