Figure 6.

p63 heterozygosity extends tumor-free and overall survival, and decreases tumor multiplicity in parous ErbB2 animals. (a) Kaplan–Meier curves of tumor-free survival and overall survival of p63+/− ErbB2 and p63+/+ ErbB2 one-time parous females; n, number of animals. (b) No difference in tumor-free and overall survival of virgin p63+/+ ErbB2 and p63+/− ErbB2 females. (c) Tumor multiplicity at endpoint (time when animal had to be killed) of p63+/− ErbB2 and p63+/+ ErbB2 females impregnated at 20 weeks. Mean±S.E.M.; n, number of animals