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. 2014 Mar 1;28(5):451–462. doi: 10.1101/gad.236745.113

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© 2014 Roset et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported), as described at http://creativecommons.org/licenses/by-nc/3.0/.

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Figure 6. — Rad50^+/46 and Rad50^+/Neo46 mice develop liver tumors. (A) Frequency of liver tumors developed by Rad50^+/+, Rad50^+/46, and Rad50^+/Neo46 mice by 18 mo of age. P-values were calculated with Fisher's exact test comparing with Rad50^+/+. (*) P ≤ 0.05; (**) P ≤ 0.01; (***)P ≤ 0.001. (B) Representative images and H&E staining of the hepatic tumors developed by Rad50^+/46 and Rad50^+/Neo46 mice. Bar, 200 μm for all images.