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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Circ Heart Fail. 2013 Dec 6;7(1):184–193. doi: 10.1161/CIRCHEARTFAILURE.113.000649

Figure 6. Anti-OPN antibody mitigates the functional decline in ILK-KO mice.

Figure 6

Mice were treated with a neutralizing anti-mouse OPN IgG or control goat IgG every other day by intraperitoneal injection, starting from FS% is approximately 40%. All mice received echocardiographic assessment before each injection. M-mode echocardiographic analyses showed that inhibiting OPN mitigates the functional decline in ILK-KO mice. Representative M-mode echocardiograms from five independent experiments are shown. Corresponding quantitative data are shown on the lower panel, *p < 0.05, ‡p<0.001 vs. control goat IgG injection at each time point, n=5.