Table 4.

ED₅₀ and Relative potency of tested compounds to Ibuprofen at 6 h.

Compound ID	ED50 (mg/kg)	Relative potency
4	60	0.66
5	54	0.74
6	90	0.44
7	69	0.58
8	75	0.53
9	105	0.38
10	120	0.33
11	117	0.34
Ibuprofen (standard)	40	1.00

ED₅₀ is the dose required to induce 50% inhibition of rat paw edema (50% anti-inflammatory effect).

ED₅₀ was calculated using instate program by plotting results at all doses levels; Ibuprofen was tested at a dose range from 25 to 100 mg/kg and tested compounds from 25 to 200 mg/kg.