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. 2014 Feb 11;5(1):e00765-13. doi: 10.1128/mBio.00765-13

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Copyright © 2014 Butts et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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FIG 5 — Anti-cryptococcal activity of triphenylethylenes correlates with calmodulin antagonism. C. neoformans strain containing fluorescently tagged Nop1-GFP and Crz1-mCherry were cultivated to logarithmic phase at 37°C with the indicated concentrations of toremifene (TOR), idoxifene, and methylene-idoxifene. As in Fig. 3B, the percentage of cells with colocalized Nop1-GFP and Crz1-mCherry under the indicated conditions is graphed. Bars show the means from three independent experiments (>100 cells counted per condition per experiment), and error bars indicate standard deviations.