Table 3.
Product | α | β | Ti | Fmax | Td (±SEM) |
---|---|---|---|---|---|
USP paddles method | |||||
R | 2.63 | 0.43 | 2.70 | 114.69 | 10.22 ± 0.68 |
A | 9.26 | 0.83 | 0.16 | 112.97 | 14.54 ± 0.36a |
B | 14.94 | 1.06 | −0.65 | 106.57 | 12.12 ± 0.09 |
C | 8.57 | 0.98 | 3.02 | 105.89 | 11.71 ± 0.26 |
D | 210.27 | 1.99 | −1.72 | 106.20 | 12.64 ± 0.31 |
Flow-through cell system | |||||
R | 7.31 | 0.77 | 3.54 | 84.16 | 16.93 ± 0.30 |
A | 22.09 | 0.88 | 3.06 | 86.32 | 37.82 ± 2.48a |
B | 40.67 | 1.17 | 2.10 | 104.66 | 24.79 ± 0.53a |
C | 23.58 | 1.09 | 2.97 | 108.07 | 20.55 ± 0.81a |
D | 97.49 | 1.56 | 1.21 | 100.26 | 19.93 ± 0.15a |
p < 0.05 vs R, Dunnett’s or Dunnett’s T3 multiple comparisons test.