Table 2. Complete Analysis of HCC Associated Factors a.
Variables | P value | Hazard Ratio | 95% CI for Hazard Ratio | |
---|---|---|---|---|
Lower | Upper | |||
Univariate Analysis | ||||
Sex | ||||
Female b | - | - | - | - |
Male | 0.00 | 9.34 | 4.33 | 20.13 |
Ages, y | ||||
< 30 b | 0.00 | - | - | - |
30 - 40 | 0.001 | 13.62 | 2.87 | 64.7 |
40 - 50 | 0.00 | 39.00 | 7.52 | 202.23 |
50 - 60 | 0.00 | 35.5 | 7.19 | 174.83 |
≥ 60 | 0.00 | 19.00 | 3.83 | 94.29 |
Genotypes B b | 0.00 | - | - | - |
C | 0.00 | 5.79 | 2.81 | 11.93 |
I | 0.06 | 5.57 | 0.92 | 33.84 |
DNA | ||||
< 104 b | - | - | - | - |
≥ 104 | 0.04 | 1.96 | 1.04 | 3.67 |
BCP Wild-type b | ||||
Mutations | 0.00 | 41.72 | 17.19 | 101.28 |
PreS deletions | ||||
Wild-type b | - | - | - | - |
Mutations | 0.00 | 14.10 | 3.23 | 61.56 |
HBeAg | ||||
Negative b | - | - | - | - |
Positive | 0.79 | 1.10 | 0.53 | 2.34 |
Anti-HBe | ||||
Negative b | - | - | - | - |
Positive | 0.07 | 1.78 | 0.96 | 3.30 |
Abnormal ALT | ||||
Negative b | - | - | - | - |
Positive | 0.03 | 2.38 | 1.10 | 5.18 |
Multivariate Analysis | ||||
Sex | 0.00 | 26.85 | 6.19 | 116.46 |
Ages, y | ||||
30 b | 0.01 | 1 | - | - |
30 - 40 | 0.00 | 29.62 | 3.08 | 284.64 |
40 - 50 | 0.00 | 56.84 | 5.65 | 571.65 |
50 - 60 | 0.00 | 53.14 | 5.08 | 555.92 |
≥ 60 | 0.01 | 18.06 | 1.87 | 174.80 |
BCP mutations | 0.00 | 66.35 | 16.32 | 273.14 |
PreS deletions | 0.06 | 5.52 | 0.97 | 31.50 |
a HBsAg asymptomatic carriers are the controls.
b The variable used for comparison.