Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Oct 30;49(2):900–915. doi: 10.1007/s12035-013-8568-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2013

Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.

PMC Copyright notice

Fig. 4 — Different migration assays using the D54MG and 86HG39 glioblastoma cell lines with ROCK inhibitor Y27632 and ROCK1/ROCK2 knockdown. In a coated radial monolayer migration assay, the cells displayed a reduction in cell migration when treated with the ROCK inhibitor Y27632 (a). Cells with a stable ROCK1 knockdown exhibited enhanced cell migration using a wound-healing assay on an uncoated surface (b), but a significant decrease in cell migration using a radial monolayer assay on a laminin-coated surface (d). Glioma cell lines with a stable ROCK2 knockdown exhibited an increase in migration on both the uncoated surface (c) and the laminin-coated surface (e) (*p < 0.05; **p < 0.001, n = 3, mean ± SEM)