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Simplified model for the assembly steps of the SSU processome. (i) The UtpA/t-Utp sub-complex assembles on the 5′ETS of the nascent pre-rRNA; (ii) UtpB then associates with the pre-rRNA followed by binding of the U3 snoRNP complex (iii); (iv) UtpC interacts with the pre-rRNA independent of UtpB and U3 snoRNP; (v) Mpp10 sub-complex assembly takes place after U3 snoRNP binding; (vi) The Bfr2–Enp2 dimer and Dbp4 incorporate the SSU processome particle.
