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. 2013 Dec 14;42(5):3009–3016. doi: 10.1093/nar/gkt1306

Figure 1.

Figure 1.

The ‘divide-and-compare’ strategy shows CHG and CHH methylations in human have no essential difference. (A) Schema of the ‘divide-and-compare’ strategy, (B) Spearman’s ranks correlation analysis between CHG and CHH methylation pairs shows the two non-CpG methylation patterns are not essentially different in human as in Arabidopsis. The corresponding pairs are xyChG and xyChH (x, y can be A, C, G or T; H indicates A, C and T are considered collectively). The x- and y-axes show methylation level ranks (1–48, from high to low) of xyChGs and xyChHs in the CHG list and CHH list, respectively. The rhos are calculated by Spearman’s ranks correlation test.