Figure 1.

Deletion detection of survival motor neuron 1 (Exon 7, 8) performed by digestion of polymerase chain reaction product with DraI and DdeI, respectively. Digestion results were analyzed on 3% agarose gel. Lane 1 and 2: Different patients without deletion in exon 7 of survival motor neuron1 (SMN1), lane 3: Patient with deletion in exon 7, lane 4: Positive control and lane 5: Normal control, Lane 6: 100 bp marker; Lane 7: Patient without deletion in exon 8 of SMN, lane 8: Patient with deletion in exon 8, lane 9: Normal control, lane 10: Positive control