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. 2014 Jan 14;110(5):1385–1391. doi: 10.1038/bjc.2013.821

Table 1. Distribution of cases and controls among men and women by socio-demographic characteristics and histological type among cases.

  Male
Female
  Cases
Controls
 
 
 
Cases
Controls
 
  N % N % ORa 95% CI P-value N % N % ORa 95% CI P-value
Total
2275
 
2780
 
 
 
 
648
 
775
 
 
 
 
Age at interview, years
<50 310 14 663 24 1.0 Ref.   160 25 167 21 1.0 Ref.  
50–60 773 34 855 31 1.9 1.6–2.3   224 35 160 21 1.5 1.1–2.1  
60–70 824 36 923 33 1.9 1.6–2.2   171 26 263 34 0.7 0.5–1.0  
⩾70
368
16
339
12
2.3
1.9–2.9
P<0.001
93
14
185
24
0.6
0.4–0.8
P<0.001
Educational levelb
Elementary school or less 675 34 521 19 1.0 Ref.   204 34 242 32 1.0 Ref.  
Middle school 869 43 1081 41 0.6 0.5–0.7   208 35 270 36 0.6 0.5–0.8  
High school 185 9 310 12 0.4 0.4–0.6   72 12 90 12 0.7 0.5–1.0  
University
274
14
752
28
0.3
0.2–0.3
P<0.001
110
19
149
20
0.5
0.4–0.8
P<0.001
Occupational exposure (list A)c
Non-exposed 1826 81 2450 88 1.0 Ref.   623 97 767 99 1.0 Ref.  
Exposed
438
19
329
12
1.8
1.5–2.1
P<0.01
21
3
8
1
3.0
1.3–6.9
P<0.001
Histological types by smoking status
Never smokers (CSI=0) 59   813         188   513        
 Squamous cell carcinoma 12 20         23 12        
 Small cell carcinoma 2 4         6 3        
 Adenocarcinoma 32 54         133 70        
 Other types 13 22         27 14        
 Multiple phenotyped             1          
Ever smokers (CSI>0) 2191   1958         457   260        
 Squamous cell carcinoma 786 36         82 18        
 Small cell carcinoma 330 15         89 19        
 Adenocarcinoma 759 35         221 48        
 Other types 336 15         70 15        
 Multiple phenotyped 20 3         5          

Abbreviations: CI=confidence interval; CSI=comprehensive smoking index; OR=odds ratio.

a

Odds ratio of lung cancer adjusted for age at interview (<50, 50–60, ⩾60) and department.

b

Educational level was not available in the summarized questionnaire.

c

Data missing for 12 men (11 cases and 1 control) and 4 women cases.

d

Multiple phenotype corresponds to tumours with several histological entities. Subjects with multiple phenotypes must be subtracted from the total to not be counted more than once.