Table 1. Distribution of cases and controls among men and women by socio-demographic characteristics and histological type among cases.
Male |
Female |
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cases |
Controls |
|
|
|
Cases |
Controls |
|
|||||||
N | % | N | % | ORa | 95% CI | P-value | N | % | N | % | ORa | 95% CI | P-value | |
Total |
2275 |
|
2780 |
|
|
|
|
648 |
|
775 |
|
|
|
|
Age at interview, years | ||||||||||||||
<50 | 310 | 14 | 663 | 24 | 1.0 | Ref. | 160 | 25 | 167 | 21 | 1.0 | Ref. | ||
50–60 | 773 | 34 | 855 | 31 | 1.9 | 1.6–2.3 | 224 | 35 | 160 | 21 | 1.5 | 1.1–2.1 | ||
60–70 | 824 | 36 | 923 | 33 | 1.9 | 1.6–2.2 | 171 | 26 | 263 | 34 | 0.7 | 0.5–1.0 | ||
⩾70 |
368 |
16 |
339 |
12 |
2.3 |
1.9–2.9 |
P<0.001 |
93 |
14 |
185 |
24 |
0.6 |
0.4–0.8 |
P<0.001 |
Educational levelb | ||||||||||||||
Elementary school or less | 675 | 34 | 521 | 19 | 1.0 | Ref. | 204 | 34 | 242 | 32 | 1.0 | Ref. | ||
Middle school | 869 | 43 | 1081 | 41 | 0.6 | 0.5–0.7 | 208 | 35 | 270 | 36 | 0.6 | 0.5–0.8 | ||
High school | 185 | 9 | 310 | 12 | 0.4 | 0.4–0.6 | 72 | 12 | 90 | 12 | 0.7 | 0.5–1.0 | ||
University |
274 |
14 |
752 |
28 |
0.3 |
0.2–0.3 |
P<0.001 |
110 |
19 |
149 |
20 |
0.5 |
0.4–0.8 |
P<0.001 |
Occupational exposure (list A)c | ||||||||||||||
Non-exposed | 1826 | 81 | 2450 | 88 | 1.0 | Ref. | 623 | 97 | 767 | 99 | 1.0 | Ref. | ||
Exposed |
438 |
19 |
329 |
12 |
1.8 |
1.5–2.1 |
P<0.01 |
21 |
3 |
8 |
1 |
3.0 |
1.3–6.9 |
P<0.001 |
Histological types by smoking status | ||||||||||||||
Never smokers (CSI=0) | 59 | 813 | 188 | 513 | ||||||||||
Squamous cell carcinoma | 12 | 20 | — | 23 | 12 | — | ||||||||
Small cell carcinoma | 2 | 4 | — | 6 | 3 | — | ||||||||
Adenocarcinoma | 32 | 54 | — | 133 | 70 | — | ||||||||
Other types | 13 | 22 | — | 27 | 14 | — | ||||||||
Multiple phenotyped | — | 1 | — | |||||||||||
Ever smokers (CSI>0) | 2191 | 1958 | 457 | 260 | ||||||||||
Squamous cell carcinoma | 786 | 36 | — | 82 | 18 | — | ||||||||
Small cell carcinoma | 330 | 15 | — | 89 | 19 | — | ||||||||
Adenocarcinoma | 759 | 35 | — | 221 | 48 | — | ||||||||
Other types | 336 | 15 | — | 70 | 15 | — | ||||||||
Multiple phenotyped | 20 | 3 | — | 5 | — |
Abbreviations: CI=confidence interval; CSI=comprehensive smoking index; OR=odds ratio.
Odds ratio of lung cancer adjusted for age at interview (<50, 50–60, ⩾60) and department.
Educational level was not available in the summarized questionnaire.
Data missing for 12 men (11 cases and 1 control) and 4 women cases.
Multiple phenotype corresponds to tumours with several histological entities. Subjects with multiple phenotypes must be subtracted from the total to not be counted more than once.