Table 3. Adverse events (n=53).
| |
Grade | |
||||
|---|---|---|---|---|---|---|
| Event | 1 | 2 | 3 | 4 | Any (%) | Grade 3–4 (%) |
| Leukopaenia |
17 |
18 |
3 |
1 |
74 |
8 |
| Neutropaenia |
8 |
5 |
14 |
5 |
60 |
36 |
| Febrile neutropaenia |
0 |
0 |
1 |
1 |
4 |
4 |
| Anaemia |
5 |
22 |
6 |
2 |
66 |
15 |
| Thrombocytopaenia |
20 |
6 |
0 |
0 |
49 |
0 |
| Anorexia |
15 |
15 |
12 |
0 |
79 |
23 |
| Fatigue |
18 |
14 |
2 |
0 |
64 |
4 |
| Nausea |
20 |
12 |
1 |
0 |
62 |
2 |
| Hypoalbuminaemia |
14 |
6 |
5 |
0 |
47 |
9 |
| Hypertension |
9 |
12 |
1 |
0 |
42 |
2 |
| Creatinine increased |
21 |
0 |
3 |
0 |
45 |
6 |
| Diarrhoea |
10 |
7 |
4 |
0 |
40 |
8 |
| Oral mucositis |
10 |
6 |
1 |
0 |
32 |
2 |
| Skin rash |
12 |
1 |
0 |
0 |
25 |
0 |
| Vomiting |
7 |
3 |
3 |
0 |
25 |
6 |
| ALT increased |
11 |
2 |
0 |
0 |
25 |
0 |
| Constipation |
7 |
4 |
0 |
0 |
21 |
0 |
| Dysgeusia |
7 |
3 |
0 |
0 |
19 |
0 |
| AST increased |
9 |
0 |
0 |
0 |
17 |
0 |
| Blood bilirubin increased |
6 |
2 |
0 |
0 |
15 |
0 |
| Edema |
6 |
2 |
0 |
0 |
15 |
0 |
| Peripheral sensory neuropathy |
1 |
5 |
0 |
0 |
11 |
0 |
| Epistaxis |
3 |
1 |
0 |
0 |
8 |
0 |
| Hiccups |
4 |
0 |
0 |
0 |
8 |
0 |
| Fever |
2 |
2 |
0 |
0 |
8 |
0 |
| Infusion-related reaction |
0 |
3 |
0 |
0 |
6 |
0 |
| Alopecia |
2 |
1 |
0 |
0 |
6 |
0 |
| Abdominal pain |
1 |
2 |
0 |
0 |
6 |
0 |
| Skin hyperpigmentation | 2 | 1 | 0 | 0 | 6 | 0 |
Abbreviations: ALT=alanine aminotransferase; AST=aspartate aminotransferase.