Table 1.
Characteristics of the AIDS-related non-Hodgkin lymphoma (NHL) study, Multicenter AIDS Cohort.
| Characteristics | post-HIV infectiona | post-AIDSb | ||||
|---|---|---|---|---|---|---|
| Cases (N= 160) |
Controls (N=160) |
P-value | Cases (N=90) |
Controls (N=90) |
P-value | |
| Age at NHL diagnosis, yr | 41 (25–60) | 39 (24–60) | 0.02 | 40 (25–58) | 39 (28–65) | 0.27 |
| Race | ||||||
| White,non-Hispanic | 83% | 88% | 0.04 | 81% | 89% | 0.40 |
| Black | 11% | 8% | 11% | 4% | ||
| Others | 6% | 4% | 8% | 7% | ||
| CD4+ T-lymphocyte counts/mm3 | ||||||
| > 3 yr pre-NHL | 387(5, 1349) | 561(3, 2030) | <0.0001 | 369(5, 1127) | 397(19, 1123) | 0.23 |
| 1–3 yr pre-NHL | 209(6, 1178) | 522(37, 1544) | <0.0001 | 114(6, 1178) | 238(9, 1123) | 0.001 |
| <1 yr pre-NHL | 74(0, 707) | 468(4, 1255) | <0.0001 | 32(0, 691) | 98(0, 1159) | 0.001 |
| Early plasma HIV-1 RNA levels, copies/mLc | 5.5 (2.0, 8.4) | 4.6 (1.8, 7.4) | <0.0001 | 5.7 (2.0, 8.4) | 5.4 (2.4, 8.5) | 0.35 |
a
cases and controls matched on post-HIV infection lymphoma-free period
b
cases and controls matched on post-AIDS lymphoma-free period
c
HIV viral load at visit closest to 18 months following HIV seroconversion or entry into study
Summary statistics are presented as median (range) or percentages and P-values were derived from Kruskal-Wallis test