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. 2014 Feb 20;2014:301879. doi: 10.1155/2014/301879

Table 4.

Effects of CS extract treatment on the level of MMP-2, MMP-9, and TIMP-1 in the liver tissue at the end of 12 weeks.

Group MMP-2 (ng/mL) MMP-9 (ng/mL) TIMP-1 (ng/mL)
Normal 2.57 ± 0.4b 8.31 ± 1.2b 1.91 ± 0.79b
TAA 8.44 ± 1.06a 46.57 ± 4.7a 7.81 ± 0.85a
CS100 2.44 ± 0.43b 8.57 ± 8.11b 1.83 ± 0.38b
CS300 2.37 ± 0.65b 8.8 ± 0.75b 2.04 ± 0.67b
CS100 + TAA 6.43 ± 0.569a,b 22.76 ± 1.78a,b 4.78 ± 1.01
CS300 + TAA 4.87 ± 0.77a,b 15.51 ± 2.44a,b 3.05 ± 0.63
SY + TAA 3.38 ± 0.525b 13.84 ± 2.8a,b 2.12 ± 0.48b

The data were stated as mean ± S.E.M. Means with different superscripts are significantly different. a P < 0.05 versus normal control group and b P < 0.05 versus TAA control group. SY stands for Silymarin (standard hepatoprotective drug).