. 2014 Feb 20;2014:639682. doi: 10.1155/2014/639682

Table 3.

Relative synonymous codon usage in human albumin superfamily members. The value in bold indicates the codons used with high frequency.

Amino acid	Codons	RSCU¹	Number	RSCU²	Number	RSCU³	Number	RSCU⁴	Number
Phe	UUU	1.43	25	1.06	17	1.30	28	1.16	11
Phe	UUC	0.57	10	0.94	15	0.70	15	0.84	8

Leu	UUA	0.94	10	1.00	10	1.20	11	0.53	5
	UUG	1.13	12	1.10	11	0.87	8	0.63	6
	CUU	1.78	19	0.90	9	1.20	11	1.16	11
	CUC	0.66	7	0.40	4	0.98	9	0.95	9
	CUA	0.38	4	0.90	9	0.65	6	1.05	10
	CUG	1.13	12	1.70	17	1.09	10	1.68	16

Ile	AUU	1.33	4	1.32	15	1.07	10	1.13	3
	AUC	1.33	4	0.71	8	0.75	7	1.13	3
	AUA	0.33	1	0.97	11	1.18	11	0.75	2

Val	GUU	1.12	12	1.47	11	1.44	13	0.89	6
	GUC	0.65	7	0.80	6	0.67	6	1.19	8
	GUA	0.74	8	0.80	6	0.67	6	1.04	7
	GUG	1.49	16	0.93	7	1.22	11	0.89	6

Ser	UCU	0.64	3	1.26	8	2.06	12	1.43	10
	UCC	1.50	7	0.47	3	0.86	5	1.29	9
	UCA	1.29	6	1.58	10	1.03	6	1.71	12
	UCG	0.64	3	0.47	3	0.00	0	0.00	0

Pro	CCU	1.67	10	1.71	9	1.71	12	1.38	9
	CCC	1.00	6	0.76	4	0.71	5	0.92	6
	CCA	1.17	7	1.52	8	1.57	11	1.54	10
	CCG	0.17	1	0.00	0	0.00	0	0.15	1

Thr	ACU	0.97	7	1.78	16	1.18	10	1.25	10
	ACC	1.24	9	0.67	6	0.82	7	1.38	11
	ACA	1.52	11	1.33	12	1.53	13	1.13	9
	ACG	0.28	2	0.22	2	0.47	4	0.25	2

Ala	GCU	1.90	30	1.20	15	1.57	11	1.82	15
	GCC	0.89	14	0.88	11	0.71	5	1.09	9
	GCA	1.08	17	1.68	21	1.29	9	0.85	7
	GCG	0.13	2	0.24	3	0.43	3	0.24	2

Tyr	UAU	1.37	13	1.06	9	1.06	9	1.13	9
Tyr	UAC	0.63	6	0.94	8	0.94	8	0.88	7

His	CAU	1.38	11	1.63	13	1.23	8	1.00	4
His	CAC	0.63	5	0.38	3	0.77	5	1.00	4

Gln	CAA	1.10	11	1.15	23	1.26	17	1.33	8
Gln	CAG	0.90	9	0.85	17	0.74	10	0.67	4

Asn	AAU	1.29	11	1.00	10	1.03	17	1.33	12
Asn	AAC	0.71	6	1.00	10	0.97	16	0.67	6

Lys	AAA	1.33	40	1.29	33	1.33	28	0.93	20
Lys	AAG	0.67	20	0.71	18	0.67	14	1.07	23

Asp	GAU	1.39	25	1.27	21	1.30	15	1.23	16
Asp	GAC	0.61	11	0.73	12	0.70	8	0.77	10

Glu	GAA	1.23	38	1.24	34	1.36	40	1.26	27
Glu	GAG	0.77	24	0.76	21	0.64	19	0.74	16

Cys	UGU	0.86	15	1.06	18	0.81	13	1.00	14
Cys	UGC	1.14	20	0.94	16	1.19	19	1.00	14

Arg	CGU	0.67	3	0.50	2	0.55	2	0.00	0
	CGC	0.22	1	0.25	1	0.27	1	0.00	0
	CGA	0.67	3	0.50	2	0.55	2	0.92	2
	CGG	0.44	2	0.25	1	0.00	0	0.46	1

Ser	AGU	1.29	6	1.54	9	0.79	5	0.86	6
Ser	AGC	0.64	3	0.51	3	1.42	9	0.71	5

Arg	AGA	2.89	13	2.75	11	3.27	12	2.31	5
Arg	AGG	1.11	5	1.75	7	1.36	5	2.31	5

Gly	GGU	0.92	3	0.75	3	0.62	4	0.29	1
	GGC	0.92	3	0.75	3	0.77	5	1.43	5
	GGA	1.85	6	1.50	6	2.00	13	1.43	5
	GGG	0.31	1	1.50	4	0.62	4	0.86	3

RSCU¹: RSCU values for ALB; RSCU²: RSCU values for AFP; RSCU³: RSCU values for AFM; RSCU⁴: RSCU values for DBP.