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. Author manuscript; available in PMC: 2015 Jan 17.
Published in final edited form as: ACS Chem Biol. 2014 Jan 6;9(1):34–44. doi: 10.1021/cb400865w

Table 1.

Representative Small Molecules Used to Reprogram Cells and Maintain hPSCs

Name Structure Known function(s)
A83-01 graphic file with name nihms553573t1.jpg TGFβ receptor ALK4/5/7 inhibitor
AMI-5 graphic file with name nihms553573t2.jpg Protein arginine N-methyltransferase inhibitor
(±)BayK 8644 (BayK) graphic file with name nihms553573t3.jpg L-type calcium channel agonist
BIX-01294 (BIX) graphic file with name nihms553573t4.jpg Histone methyltransferase G9a inhibitor
CHIR99021 (CHIR) graphic file with name nihms553573t5.jpg Glycogen synthase kinase 3β inhibitor
3-Deazaneplanocin A (DZNep) graphic file with name nihms553573t6.jpg Histone methylation inhibitor
Forskolin graphic file with name nihms553573t7.jpg PKA activator
Kenpaullone graphic file with name nihms553573t8.jpg GSK3 and CDK1/cyclin B inhibitor
Parnate graphic file with name nihms553573t9.jpg Lysine specific demethylase 1 inhibitor
PD0325901 (PD) graphic file with name nihms553573t10.jpg MEK inhibitor
PS48 graphic file with name nihms553573t11.jpg PDK1 activator
E-616452 graphic file with name nihms553573t12.jpg TGFβ Receptor I kinase inhibitor
RG108 graphic file with name nihms553573t13.jpg DNA methyltransferase inhibitor
SB431542 graphic file with name nihms553573t14.jpg Activin receptor-like kinase 4/5/7 inhibitor
Sodium butyrate (NaB) graphic file with name nihms553573t15.jpg Histone deacetylase inhibitor
Thiazovivin (Tzv) graphic file with name nihms553573t16.jpg ROCK inhibitor
Pyrintegrin (Ptn) graphic file with name nihms553573t17.jpg Unknown
Valproic acid (VPA) graphic file with name nihms553573t18.jpg Histone deacetylase inhibitor