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Duration of anesthesia (LRR) induced by tail vein injection of alphaxalone (6), and ent-7 and ent-9. The compounds were dissolved in 22.5% aqueous 2-(hydroxypropyl)-β-cyclodextrin. For compound ent-9, serial dilutions of the 8 mg/kg stock solution with 0.9% saline were made to obtain the lower doses tested.
