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. Author manuscript; available in PMC: 2015 Jan 9.
Published in final edited form as: J Med Chem. 2013 Dec 24;57(1):171–190. doi: 10.1021/jm401577c

Figure 6.

Figure 6

Correlation between compound logP and log TBPS IC50 values for compounds with reported IC50 values below 500 nM. Red symbols represent enantiomers (“e”). Black symbols represent natural compounds. There was no correlation between logP and log TBPS IC50 (or between logP and TBPS IC50, Supplemental Material Figure S3).