Table 1. YAP1 expression is positively correlated with smoking status of ESCC patients1.
| strong positivity of YAP1(+ + +) | median positivity of YAP1 (+ +) | weak positivity of YAP1 (+) | YAP1 negative (−) | Total cancer number | |
| Non-Smokers2 | 3 | 5 | 20 | 1 | 29 |
| Smokers3 | 7 | 24 | 20 | 3 | 54 |
| Peri tumor tissue | 0 | 0 | 15 | 68 | 83 |
(P<0.05, χ2 = 6.74).
1
83 ESCC clinical samples were examined for YAP1 expression using immunohistochemical approach as described in Materials and Methods.
2
Strong and median YAP1 staining in Non-smoker ESCC patients (8/29, 27.6%).
3
Strong and median YAP1 staining in smoker ESCC patients (31/54, 57.4%).
Correlations between the subgroups of staining and cigarette smoking were calculated using the Pearson and χ2 test.