. Author manuscript; available in PMC: 2014 Mar 12.

Published in final edited form as: Sci Signal. 2013 Apr 30;6(273):ra28.1–15. doi: 10.1126/scisignal.2003884

Table 1.

KDM4A is highly abundant in human SCC lymph node metastasis

	KDM4A				JUN				FOSL1

	0	+	++	+++	0	+	++	+++	0	+	++	+++

Normal	45.71% (16/35)	42.86% (15/35)	11.43% (4/35)	0% (0/35)	62.86% (22/35)	37.14% (13/35)	0% (0/35)	0% (0/35)	45.71% (16/35)	42.86% (15/35)	11.43% (4/35)	0% (0/35)
SCC^**	7.35% (5/68)	26.47% (18/68)	39.71% (27/68)	26.47% (18/68)	16.18% (11/68)	20.58% (14/68)	41.18% (28/68)	22.06% (15/68)	17.65% (12/68)	35.29% (24/68)	27.94% (19/68)	19.12% (13/68)
LN^*	0% (0/34)	11.76% (4/34)	32.36% (11/34)	55.88% (19/34)	2.94% (1/34)	17.65% (6/34)	26.47% (9/34)	52.94% (18/34)	2.94% (1/34)	11.76% (4/34)	47.06% (16/34)	38.24% (13/34)

Normal human adjacent epithelial tissues (Normal; n = 35), human primary SCC without lymph node metastasis (SCC; n = 68), and metastatic SCC in lymph node (LN; n = 34) were stained for KDM4A, JUN, and FOSL1. The staining intensity was scored as: 0, negative staining; +, weak staining; ++, moderate staining; +++ strong staining.

^**

P<0.01 SCC versus normal;

P<0.05 LN versus SCC; Wilcoxon rank sum test.