Table 1. Demographic Characteristics.
| Subjects | Age (Mo) | Sex | ADOS | CARS | SCQ | IQ | ||||
| A | B | Diagnosis | FSIQ | VIQ | PIQ | |||||
| Patients with ASD | ||||||||||
| ASD 1 | 204 | F | 3 | 4 | ASD | 21 | 22 | 88 | 92 | 74 |
| ASD 2 | 198 | M | 2 | 9 | ASD | 26.5 | 29 | 77 | 82 | 83 |
| ASD 3 | 202 | M | 3 | 9 | Autism | 23 | 26 | 71 | 75 | 74 |
| ASD 4 | 215 | F | 5 | 13 | Autism | 37.5 | 14 | 80 | 77 | 82 |
| ASD 5 | 205 | M | 4 | 12 | Autism | 29 | 16 | 71 | 76 | 62 |
| ASD 6 | 158 | M | 4 | 11 | Autism | 30.5 | 18 | 79 | 73 | 84 |
| ASD 7 | 160 | M | 5 | 6 | Autism | 34.5 | 22 | 85 | 90 | 75 |
| ASD 8 | 209 | M | 3 | 6 | ASD | 21 | 23 | 75 | 73 | 74 |
| ASD 9 | 212 | M | 4 | 9 | Autism | 26.5 | 25 | 93 | 96 | 89 |
| ASD 10 | 161 | M | 4 | 4 | ASD | 21.5 | 22 | 78 | 72 | 81 |
| mean±SDa | 192.4±23.1 | 8M/2F | 27.1±5.8 | 21.7±4.6 | 81.5±8.9 | 80.6±8.9 | 77.8±7.6 | |||
| Healthy Control Subjects | ||||||||||
| HC1 | 191 | M | - | - | Healthy | 16 | 3 | 100 | 103 | 95 |
| HC2 | 202 | M | - | - | Healthy | 15 | 2 | 110 | 110 | 107 |
| HC3 | 216 | M | - | - | Healthy | 16.5 | 4 | 117 | 115 | 116 |
| HC4 | 156 | F | - | - | Healthy | 15.5 | 3 | 116 | 125 | 99 |
| HC5 | 155 | M | - | - | Healthy | 15 | 2 | 109 | 114 | 100 |
| HC6 | 118 | M | - | - | Healthy | 15 | 1 | 109 | 108 | 109 |
| HC7 | 158 | M | - | - | Healthy | 17 | 2 | 94 | 97 | 92 |
| HC8 | 214 | M | - | - | Healthy | 15 | 1 | 94 | 90 | 102 |
| HC9 | 178 | M | - | - | Healthy | 15.5 | 2 | 93 | 97 | 89 |
| HC10 | 190 | F | - | - | Healthy | 15 | 3 | 120 | 119 | 116 |
| mean±SDb | 178.8±32.5 | 8M/2F | 15.5±0.7 | 2.3±0.9 | 106.2±10.2 | 107.8±8.9 | 102.5±9.4 | |||
| Statistics | U = 33.0, z = 1.3, p = 0.19 | F = 15.5, df = 1, p<0.01 | F = 53.4, df = 1, p<0.01 | U = 3.50, z = 3.51, p<0.01 | U = 2.50, z = 3.59, p<0.01 | U = 03.50, z = 3.74, p<0.01 | ||||
| a vs b | ||||||||||
Mann-Whitney U test, SCQ: Social Communication Questionnaire, FSIQ: IQ total, VIQ: verbal IQ, PIQ: performance IQ, A: ADOS-A (Autism Diagnostic Observation Schedule-A): communication score, B: ADOS-B: social score, the threshold scores for a diagnosis of autism on the ADOS are 3 and 6 for communication and social symptoms, respectively. Threshold scores for a less severe diagnosis of ASD on the ADOS are 2 and 4 for communication and social symptoms, respectively. Mo: months, CARS: Child Autism Rating Scale, ASD: autism spectrum disorders, HC: healthy comparison subjects.