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. 2014 Mar 12;9(3):e91487. doi: 10.1371/journal.pone.0091487

Figure 4. Long-term retention and stability experiments.

Figure 4

The long-term stability of HSPC/Chol/DSPE-PEG 2000 (5.5:4:0.5 mol/mol) liposomes loaded with EPI via the EDTA ion gradient method and stored at 4°C for 24 months in PBS buffer at a drug concentration of 1.5 mg/ml illustrated in panel A as drug retention and in panel B as liposome size (▪, left axis) or polydispersity index changes (•, right axis). The bars represent the means +/− SD of three analyses. If not shown, then the errors bar were less than 5%.