Table 2. Survival time of mice treated with free or liposomal EPI at a dose of 6 or 9/kg.
Group | Median survival time SD | ILS% | N |
Control | 47 | - | 8 |
Free EPI 6 mg/kg | 49 | 3 | 8 |
Free EPI 9 mg/kg | 16 | −66 | 8 |
Liposomal EPI 6 mg/kg | 56 | 19 | 7 |
Liposomal EPI 9 mg/kg | 68* | 45 | 7 |
N – number of mice per group, *p<0.05 as compared to the results for mice treated with 9 mg/kg free EPI (Kruskal-Wallis multiple comparison test). ILS – Increased Life Span.