Table 2. Assessment of the risk of bias according to the Cochrane Collaboration's tool.

RE-LY, 2009	+	+	−	+	+	+
ROCKET, 2011	+	+	+	+	+	+
ARISTOTLE, 2011	+	+	+	+	+	+
	Random sequence generation	Allocation concealment	Blinding of participants and personnel	Blinding of outcome assessment	Incomplete outcome data	Selective reporting

+: Low risk of bias; −: high risk of bias