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. 2014 Mar 12;9(3):e91323. doi: 10.1371/journal.pone.0091323

Figure 1. Design of chimeric proteins from PR and GR.

Figure 1

(a) Schematic drawing of the secondary structure of the chimera. The GR sequence of the E-helix (…ELS) is connected to the third loop of bovine Rh, which further continues to the F-helix (…VQT) of GR. (b) We removed the sequence of RSLVRQPAA in the E–F loop from GR (SACNTASPA from PR), and inserted constructs of the third loop of bovine Rh. In the second loop, we removed the sequence of LTLPAKEAR in the C–D loop from GR. The A178 position of PR and the ERY residue of bovine Rh are emphasized in bold.