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. 2014 Mar 12;9(3):e91492. doi: 10.1371/journal.pone.0091492

Figure 3. Allo-HSCT and aGVHD effects on CD34+Lin−CD10+CD24− cells gene expression and plasma concentrations of chemokines and cytokines are associated with alterations to BM egress, thymic homing and T-cell commitment.

Figure 3

(A) Relative CD34+Lin−CD10+CD24− mRNA expression by quantitative RT-PCR of CXCR4 and plasma concentration of CXCL12. (B) RT-PCR quantification of CCR7, CCR9 and plasmatic dosage of their respective ligands CCL19, CCL21 and CCL25. (C) RT-PCR quantification of IL7RA and GATA3 and plasmatic dosage of IL-7 in healthy donors (HD, white boxes/circles), patients with grade II-IV aGVHD (Gr II-IV, black boxes/circles), patients with grade 0-I aGVHD (Gr 0-1, grey boxes/circles). *p<0.05, **p<0.01, ***p<0.001, NS: Not Significant (Mann-Whitney).