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A. Middle ear mucosa of an uninfected control animal. B. The middle ear of an animal infected with the ΔtoxAvapA mutant for 4 days. Note the characteristic goblet cell hyperplasia associated with a productive NTHi infection. C. The middle ear of an animal infected with the wild type parent strain 86-028NP. The middle ear lumen is at the top of each micrograph.
