Table 2. Number of viable gentamicin-resistant internalized bacteria that survived over time in the EpiAirway human tissue model (n = 6).
Day | CFU/ml WT (±SD) | CFU/ml ΔtoxAvapA (±SD) | p value | % WT |
2 | 8.9E+05 (1.6E+06) | 6.2E+04 (5.9E+04) | 0.047 | 7.0 |
4 | 7.3E+05 (4.2E+05) | 4.3E+05 (1.3E+05) | 0.038 | 58.9 |
8 | 2.5E+06 (1.4E+06) | 9.5E+05 (6.8E+05) | 0.014 | 38.2 |