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The association between p16 inactivation and EGFR, KRAS, STK11 mutations and smoke exposure. The frequency of p16 WT, HD, methylation and point mutation cases in each mutation type or smoking exposure group are presented in the bar graphs for cell lines, tumors or combined. * indicates statistically significant value. (for cell lines, p=0.025; for tumors, p=0.025; for combined, p=0.003)
