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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Clin Lymphoma Myeloma Leuk. 2013 Sep;13(0 2):S355–S362. doi: 10.1016/j.clml.2013.05.024

Figure 4. Effect of protein synthesis inhibition by SGI-1776 and bendamustine and their combination in B-cell lymphoma cells.

Figure 4

Cells from (A) JeKo-1 cell line, or primary (B) MCL and (C) SMZL samples were treated with DMSO alone, or 5μM, 10μM bendamustine, 5μM SGI-1776, or 5μM, 10μM bendamustine combined with 5μM SGI-1776 for 24hr, then cells were incubated with [4,5-3H]-L-leucine at 0.8μCi/mL concentration for 45min. Radioactive incorporation was then measured by scintillation count and values were recorded as DPM/cell and normalized to DMSO control. Experiments in JeKo-1 were performed in triplicate and presented as mean ± SEM.