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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Dev Biol. 2014 Jan 17;387(1):1–14. doi: 10.1016/j.ydbio.2014.01.009

Figure 10. Loss of p53 from NPCMdm2−/− kidneys can rescue metanephrogenesis. (A, C, E, G).

Figure 10

Gross morphology of kidneys at P0 ; (B, D, F, H) H & E staining of kidney sections from corresponding genotypes. (A, B) NPCp53+/+; Mdm2+/+ wild type control; (C, D) NPCp53+/+; Mdm2−/− homozygous null mutant for Mdm2 but wild type for p53; (E, F) NPCp53+/−; Mdm2−/− homozygous null mutant for Mdm2 but heterozgyous for p53; (G, H) NPCp53−/−; Mdm2−/− compound homozygous null mutant for Mdm2 and p53.