Table 1.
Age group-adjusted odds ratio estimates for established pancreas cancer risk factors
| Cases | Controls | AOR | |||
|---|---|---|---|---|---|
| Characteristic | N=345 | % | N=1285 | (95% CI) | |
| Family History of Pancreas Cancera | |||||
| No | 298 | 91 | 1168 | 96 | 1.00 |
| Yes | 29 | 9 | 49 | 4 | 2.36 (1.46-3.82) |
| Pancreatitis | |||||
| No | 325 | 95 | 1261 | 99 | 1.00 |
| Yes | 17 | 5 | 15 | 1 | 4.44 (2.18-9.05) |
| Diabetes (Type 2)b | |||||
| No | 270 | 78 | 1113 | 87 | 1.00 |
| Yes | 74 | 22 | 162 | 13 | 1.74 (1.28-2.38) |
| Blood Type | |||||
| Type O | 64 | 19 | 342 | 28 | 1.00 |
| Non-Type O | 98 | 29 | 347 | 28 | 1.56 (1.10-2.22) |
| Don't know | 173 | 52 | 537 | 44 | — |
| Cigarette Smoking | |||||
| Never | 135 | 39 | 581 | 45 | 1.00 |
| Ever | 207 | 61 | 701 | 55 | 1.28 (1.00-1.63) |
| >0-<8.5 pack years | 54 | 17 | 224 | 18 | 1.06 (0.74-1.50) |
| 8.5-<22 pack years | 60 | 18 | 238 | 19 | 1.12 (0.80-1.58) |
| ≥22 pack years | 78 | 24 | 230 | 18 | 1.42 (1.03-1.95) |
| Alcohol Consumption | |||||
| Never | 120 | 35 | 415 | 33 | 1.00 |
| Former | 27 | 8 | 89 | 7 | 1.06 (0.66-1.72) |
| Current | 193 | 57 | 769 | 60 | 0.87 (0.67-1.13) |
| Light to moderate (1-20 drinks/wk) | 155 | 47 | 666 | 54 | 0.81 (0.62-1.06) |
| Heavy (21+ drinks/wk) | 30 | 9 | 74 | 6 | 1.41 (0.88-2.26) |
| Body Mass Index (kg/m2)c | |||||
| <25.0 | 119 | 35 | 412 | 32 | 1.00 |
| 25.0-<30.0 | 110 | 33 | 522 | 41 | 0.74 (0.55-0.99) |
| ≥30.0 | 107 | 32 | 343 | 27 | 1.14 (0.84-1.54) |
| Gender | |||||
| Male | 175 | 51 | 680 | 53 | — |
| Female | 170 | 49 | 605 | 47 | — |
| Age (y)d | |||||
| <60 | 86 | 25 | 450 | 35 | — |
| 60-64 | 74 | 21 | 288 | 22 | — |
| 65-69 | 65 | 19 | 221 | 17 | — |
| 70-89 | 120 | 35 | 326 | 25 | — |
AOR, age group-adjusted odds ratio; CI, confidence interval.
a
- First degree relatives
b
- Prior to one year before questionnaire completion
c
– One year before questionnaire completion
d
- Age at pancreas cancer diagnosis for cases; age at questionnaire completion for controls