Figure 4.
Absence of SAA does not alter atherosclerotic lesion formation in the aortic sinuses of male apoE-/- mice fed a Western diet for 12 weeks. Atherosclerotic lesion area in aortic root sections of male mice fed a diet enriched in saturated fats for 12 weeks were determined after ORO staining. A: Circles represent the means and bars the SEM of sections located ∼ 80 μm apart starting 400 μm before the transition and ending 400μm after the transition. The transition zone is defined by the disappearance of the valve cusps and is labeled “0” on the x-axis, n=5. B: Representative Oil Red O stained sections at the transition zone from 2 SAAWT mice and 2 SAAKO mice.